Activation of the Coagulation System in Polycythemia

Thrombosis is one of the major complicafiltration on 4% agarose. Fibrin degradations of polycythemia vera. Seventeen pation products were normal and antitients with polycythemia vera in good thrombin III levels were slightly elevated, hematologic control were evaluated for It appears that patients with polycythemia abnormalities of the coagulation system. vera have chronic activation of the coaguActivation of the intrinsic coagulation lation system, probably initiated by accascade was suggested by low levels of tivation of factor XII. No correlation factor XII, prekallikrein, and kallikrein between the degree of coagulation abinhibitors in 12 of 17 patients. The group normalities and thromboembolic comalso demonstrated a significant increase in plications was evident in this group of soluble fibrin complexes using plasma gel patients.